Receding Horizon Control of HIV
نویسندگان
چکیده
This paper describes a model of the immunologic response of the human immunodeficiency virus (HIV) in individuals. It then illustrates how a Receding Horizon Control (RHC) methodology can be used to drive the system to a stable equilibrium in which a strong immune response controls the viral load in the absence of drug treatment. We also illustrate how this feedback methodology can overcome unplanned treatment interruptions, inaccurate or incomplete data and imperfect model specification. We consider how ideas from stochastic estimation can be used in conjunction with RHC to create a robust treatment methodology.
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